ELISA試劑盒我們提供的抗體用于實(shí)驗(yàn)研究，而不用于診臨床斷或治療程序。
細(xì)胞酪氨酸轉(zhuǎn)氨酶抗體Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名稱 Anti-ATTY
中文名稱 細(xì)胞酪氨酸轉(zhuǎn)氨酶抗體
別 名 TYROSINE AMINOTRANSFERASE; tyrosine aminotransferase; MGC37772; MGC37789; MGC37790; MGC37819; MGC37828; MGC37842; TAT; ATTY_HUMAN; L-tyrosine:2-oxoglutarate aminotransferase; TAT; Tyrosine aminotransferase; Tyrosine aminotransferase, cytosolic.
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
細(xì)胞酪氨酸轉(zhuǎn)氨酶抗體抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Cow
產(chǎn)品類型 一抗
研究領(lǐng)域 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 合成與降解
蛋白分子量 predicted molecular weight: 50kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Tat
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia （type II, Richner-Hanhart syndrome）, a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked.
Function : Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate （in vitro）. Has no transaminase activity towards phenylalanine.
Subunit : Homodimer （Probable）.
ELISA試劑盒DISEASE : Defects in TAT are the cause of tyrosinemia type 2 （TYRO2） [MIM:276600]; also known as Richner-Hanhart syndrome. TYRO2 is an inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, and oculocutaneous manifestations. Typical features include palmoplantar keratosis, painful corneal ulcers, and mental retardation.
Similarity : Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
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